Movement Disorder Society Unified Parkinson Disease Rating Scale experiences in daily living: Longitudinal changes and correlation with other assessments
Identifieur interne : 000F72 ( Main/Exploration ); précédent : 000F71; suivant : 000F73Movement Disorder Society Unified Parkinson Disease Rating Scale experiences in daily living: Longitudinal changes and correlation with other assessments
Auteurs : Anthony E. Lang [Canada] ; Shirley Eberly [États-Unis] ; Christopher G. Goetz [États-Unis] ; Glenn Stebbins [États-Unis] ; David Oakes [États-Unis] ; Ken Marek [États-Unis] ; Bernard Ravina [États-Unis] ; Caroline M. Tanner [États-Unis] ; Ira Shoulson [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2013-12.
English descriptors
- KwdEn :
- Activities of Daily Living, Aged, Aged, 80 and over, Disease Progression, Female, Humans, Longitudinal Studies, Male, Mental Status Schedule, Middle Aged, Parkinson Disease (diagnosis), Parkinson Disease (psychology), Severity of Illness Index, Societies, Medical (standards), Statistics as Topic, Time Factors.
- MESH :
- diagnosis : Parkinson Disease.
- psychology : Parkinson Disease.
- standards : Societies, Medical.
- Activities of Daily Living, Aged, Aged, 80 and over, Disease Progression, Female, Humans, Longitudinal Studies, Male, Mental Status Schedule, Middle Aged, Severity of Illness Index, Statistics as Topic, Time Factors.
Abstract
The Movement Disorder Society (MDS) commissioned a revision of the UPDRS with the goals of improving instructions and definitions, more accurately evaluating milder features, and assessing patient‐reported outcomes and nonmotor features. To date, no study has evaluated longitudinal changes in components of the MDS‐UPDRS over time or correlated these with changes in other scales of various symptoms. We assessed Parts I and II of the MDS‐UPDRS (non‐Motor and Motor Experiences of Daily Living [nM‐EDL, M‐EDL]) as well as a number of other scales of motor, cognitive and behavioral function in a large population of patients (n = 383) with early‐ to mid‐stage Parkinson's disease (PD) who had previously participated in a trial of a putative disease‐modifying agent. Both parts of a MDS‐UPDRS showed significant change over the 3‐year follow‐up period, with M‐EDL scores declining to a greater extent than nM‐EDL. Both the scores and their changes over time correlated relatively well with other rating scales of similar disease aspects. Modest correlations with the original version of the UPDRS supported the increased attention to nonmotor symptoms as well as milder levels of severity in the MDS‐UPDRS. The M‐EDL was much more sensitive to change over time in these early‐ to mid‐stage patients than the original UPDRS Activities of Daily Living (ADL) scale. Finally, we showed no change over time in a small group of individuals with dopamine transporter single‐photon emission computed tomography scans without evidence for dopamine deficiency. The nM‐EDL and M‐EDL components of the MDS‐UPDRS provide an effective, relevant measure of change in the broad spectrum of symptoms of PD over the first decade of the disease. © 2013 International Parkinson and Movement Disorder Society
Url:
DOI: 10.1002/mds.25671
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001047
- to stream Istex, to step Curation: 001047
- to stream Istex, to step Checkpoint: 000090
- to stream PubMed, to step Corpus: 000833
- to stream PubMed, to step Curation: 000833
- to stream PubMed, to step Checkpoint: 000833
- to stream Ncbi, to step Merge: 001592
- to stream Ncbi, to step Curation: 001592
- to stream Ncbi, to step Checkpoint: 001592
- to stream Main, to step Merge: 000F84
- to stream Main, to step Curation: 000F72
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Movement Disorder Society Unified Parkinson Disease Rating Scale experiences in daily living: Longitudinal changes and correlation with other assessments</title><author><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E." last="Lang">Anthony E. Lang</name></author><author><name sortKey="Eberly, Shirley" sort="Eberly, Shirley" uniqKey="Eberly S" first="Shirley" last="Eberly">Shirley Eberly</name></author><author><name sortKey="Goetz, Christopher G" sort="Goetz, Christopher G" uniqKey="Goetz C" first="Christopher G." last="Goetz">Christopher G. Goetz</name></author><author><name sortKey="Stebbins, Glenn" sort="Stebbins, Glenn" uniqKey="Stebbins G" first="Glenn" last="Stebbins">Glenn Stebbins</name></author><author><name sortKey="Oakes, David" sort="Oakes, David" uniqKey="Oakes D" first="David" last="Oakes">David Oakes</name></author><author><name sortKey="Marek, Ken" sort="Marek, Ken" uniqKey="Marek K" first="Ken" last="Marek">Ken Marek</name></author><author><name sortKey="Ravina, Bernard" sort="Ravina, Bernard" uniqKey="Ravina B" first="Bernard" last="Ravina">Bernard Ravina</name></author><author><name sortKey="Tanner, Caroline M" sort="Tanner, Caroline M" uniqKey="Tanner C" first="Caroline M." last="Tanner">Caroline M. Tanner</name></author><author><name sortKey="Shoulson, Ira" sort="Shoulson, Ira" uniqKey="Shoulson I" first="Ira" last="Shoulson">Ira Shoulson</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:9F5E8D5A9D0EF4CE83A620D2BC8EE019CB4E86AD</idno><date when="2013" year="2013">2013</date><idno type="doi">10.1002/mds.25671</idno><idno type="url">https://api-v5.istex.fr/document/9F5E8D5A9D0EF4CE83A620D2BC8EE019CB4E86AD/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001047</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001047</idno><idno type="wicri:Area/Istex/Curation">001047</idno><idno type="wicri:Area/Istex/Checkpoint">000090</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000090</idno><idno type="wicri:doubleKey">0885-3185:2013:Lang A:movement:disorder:society</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:24123383</idno><idno type="wicri:Area/PubMed/Corpus">000833</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000833</idno><idno type="wicri:Area/PubMed/Curation">000833</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000833</idno><idno type="wicri:Area/PubMed/Checkpoint">000833</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000833</idno><idno type="wicri:Area/Ncbi/Merge">001592</idno><idno type="wicri:Area/Ncbi/Curation">001592</idno><idno type="wicri:Area/Ncbi/Checkpoint">001592</idno><idno type="wicri:Area/Main/Merge">000F84</idno><idno type="wicri:Area/Main/Curation">000F72</idno><idno type="wicri:Area/Main/Exploration">000F72</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Movement Disorder Society Unified Parkinson Disease Rating Scale experiences in daily living: Longitudinal changes and correlation with other assessments</title><author><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E." last="Lang">Anthony E. Lang</name><affiliation wicri:level="4"><country xml:lang="fr">Canada</country><wicri:regionArea>Morton and Gloria Shulman Movement Disorders Clinic and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital, University of Toronto, Ontario, Toronto</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Canada</country></affiliation></author><author><name sortKey="Eberly, Shirley" sort="Eberly, Shirley" uniqKey="Eberly S" first="Shirley" last="Eberly">Shirley Eberly</name><affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics and Computational Biology, University of Rochester, New York, Rochester</wicri:regionArea><wicri:noRegion>Rochester</wicri:noRegion></affiliation></author><author><name sortKey="Goetz, Christopher G" sort="Goetz, Christopher G" uniqKey="Goetz C" first="Christopher G." last="Goetz">Christopher G. Goetz</name><affiliation wicri:level="3"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Illinois, Chicago</wicri:regionArea><placeName><settlement type="city">Chicago</settlement><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Stebbins, Glenn" sort="Stebbins, Glenn" uniqKey="Stebbins G" first="Glenn" last="Stebbins">Glenn Stebbins</name><affiliation wicri:level="3"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Illinois, Chicago</wicri:regionArea><placeName><settlement type="city">Chicago</settlement><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Oakes, David" sort="Oakes, David" uniqKey="Oakes D" first="David" last="Oakes">David Oakes</name><affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics and Computational Biology, University of Rochester, New York, Rochester</wicri:regionArea><wicri:noRegion>Rochester</wicri:noRegion></affiliation></author><author><name sortKey="Marek, Ken" sort="Marek, Ken" uniqKey="Marek K" first="Ken" last="Marek">Ken Marek</name><affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Neurodegenerative Disorders, Connecticut, New Haven</wicri:regionArea><wicri:noRegion>New Haven</wicri:noRegion></affiliation></author><author><name sortKey="Ravina, Bernard" sort="Ravina, Bernard" uniqKey="Ravina B" first="Bernard" last="Ravina">Bernard Ravina</name><affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biogen Idec, Massachusetts, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Tanner, Caroline M" sort="Tanner, Caroline M" uniqKey="Tanner C" first="Caroline M." last="Tanner">Caroline M. Tanner</name><affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Parkinson's Institute, Sunnyvale, California, USA, and Department of Health Research and Policy, Stanford University, California, Palo Alto</wicri:regionArea><wicri:noRegion>Palo Alto</wicri:noRegion></affiliation></author><author><name sortKey="Shoulson, Ira" sort="Shoulson, Ira" uniqKey="Shoulson I" first="Ira" last="Shoulson">Ira Shoulson</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Washington (État)</region></placeName><wicri:cityArea>Georgetown University Medical Center, DC</wicri:cityArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><date type="published" when="2013-12">2013-12</date><biblScope unit="volume">28</biblScope><biblScope unit="issue">14</biblScope><biblScope unit="page" from="1980">1980</biblScope><biblScope unit="page" to="1986">1986</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">9F5E8D5A9D0EF4CE83A620D2BC8EE019CB4E86AD</idno><idno type="DOI">10.1002/mds.25671</idno><idno type="ArticleID">MDS25671</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Activities of Daily Living</term><term>Aged</term><term>Aged, 80 and over</term><term>Disease Progression</term><term>Female</term><term>Humans</term><term>Longitudinal Studies</term><term>Male</term><term>Mental Status Schedule</term><term>Middle Aged</term><term>Parkinson Disease (diagnosis)</term><term>Parkinson Disease (psychology)</term><term>Severity of Illness Index</term><term>Societies, Medical (standards)</term><term>Statistics as Topic</term><term>Time Factors</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Societies, Medical</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Activities of Daily Living</term><term>Aged</term><term>Aged, 80 and over</term><term>Disease Progression</term><term>Female</term><term>Humans</term><term>Longitudinal Studies</term><term>Male</term><term>Mental Status Schedule</term><term>Middle Aged</term><term>Severity of Illness Index</term><term>Statistics as Topic</term><term>Time Factors</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">The Movement Disorder Society (MDS) commissioned a revision of the UPDRS with the goals of improving instructions and definitions, more accurately evaluating milder features, and assessing patient‐reported outcomes and nonmotor features. To date, no study has evaluated longitudinal changes in components of the MDS‐UPDRS over time or correlated these with changes in other scales of various symptoms. We assessed Parts I and II of the MDS‐UPDRS (non‐Motor and Motor Experiences of Daily Living [nM‐EDL, M‐EDL]) as well as a number of other scales of motor, cognitive and behavioral function in a large population of patients (n = 383) with early‐ to mid‐stage Parkinson's disease (PD) who had previously participated in a trial of a putative disease‐modifying agent. Both parts of a MDS‐UPDRS showed significant change over the 3‐year follow‐up period, with M‐EDL scores declining to a greater extent than nM‐EDL. Both the scores and their changes over time correlated relatively well with other rating scales of similar disease aspects. Modest correlations with the original version of the UPDRS supported the increased attention to nonmotor symptoms as well as milder levels of severity in the MDS‐UPDRS. The M‐EDL was much more sensitive to change over time in these early‐ to mid‐stage patients than the original UPDRS Activities of Daily Living (ADL) scale. Finally, we showed no change over time in a small group of individuals with dopamine transporter single‐photon emission computed tomography scans without evidence for dopamine deficiency. The nM‐EDL and M‐EDL components of the MDS‐UPDRS provide an effective, relevant measure of change in the broad spectrum of symptoms of PD over the first decade of the disease. © 2013 International Parkinson and Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Canada</li><li>États-Unis</li></country><region><li>Illinois</li><li>Ontario</li><li>Washington (État)</li></region><settlement><li>Chicago</li><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><country name="Canada"><region name="Ontario"><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E." last="Lang">Anthony E. Lang</name></region><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E." last="Lang">Anthony E. Lang</name></country><country name="États-Unis"><noRegion><name sortKey="Eberly, Shirley" sort="Eberly, Shirley" uniqKey="Eberly S" first="Shirley" last="Eberly">Shirley Eberly</name></noRegion><name sortKey="Goetz, Christopher G" sort="Goetz, Christopher G" uniqKey="Goetz C" first="Christopher G." last="Goetz">Christopher G. Goetz</name><name sortKey="Marek, Ken" sort="Marek, Ken" uniqKey="Marek K" first="Ken" last="Marek">Ken Marek</name><name sortKey="Oakes, David" sort="Oakes, David" uniqKey="Oakes D" first="David" last="Oakes">David Oakes</name><name sortKey="Ravina, Bernard" sort="Ravina, Bernard" uniqKey="Ravina B" first="Bernard" last="Ravina">Bernard Ravina</name><name sortKey="Shoulson, Ira" sort="Shoulson, Ira" uniqKey="Shoulson I" first="Ira" last="Shoulson">Ira Shoulson</name><name sortKey="Stebbins, Glenn" sort="Stebbins, Glenn" uniqKey="Stebbins G" first="Glenn" last="Stebbins">Glenn Stebbins</name><name sortKey="Tanner, Caroline M" sort="Tanner, Caroline M" uniqKey="Tanner C" first="Caroline M." last="Tanner">Caroline M. Tanner</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000F72 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000F72 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:9F5E8D5A9D0EF4CE83A620D2BC8EE019CB4E86AD
|texte= Movement Disorder Society Unified Parkinson Disease Rating Scale experiences in daily living: Longitudinal changes and correlation with other assessments
}}
| This area was generated with Dilib version V0.6.29. |  |